Case 217. EBV-associated hemophagocytic syndrome (20 y-o F)

       
  Bone marrow aspirate from the young, manifesting fever, cervical lymphadenopathy, pancytopenia and atypical lymphocytosis (5%).  
       

 

  Leukophagocytosis by macrophages is evident (HE). Supression of normal hematopoetic cells is associated. Elevation of IgG-type antibody to EBV is compatible with EB-VAHS.