Case 179. Protothecosis (66 y-o M)

       
  Biopsy from an irregular infiltrative nodule on the dorsum of the hand of a farmer who cultivates Japanese oranges  
       

 

  Closer view of necrotizing epithelioid granuloma in the dermis, resembling granulomatous lesions of other causes (HE). Pathogens are difficult to see in H&E preparation in this case.