Case 35. 

Crohn-like longitudinal colonic ulcer in chronic granulomatous disease (8 y-o M)
       
  Colon surgically resected for intractable ulceration seen in chronic granulomatous disease  
       

 

  Epithelioid cells are clustered in the granuloma (HE, high power). E. coli antigens are not demonstrated by immunostaining.