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Case 223. MRSA endocarditis (55 y-o M)
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| Autopsied heart with large verruca formation and ulceration in the aortic valve in case of disseminated malignancy |
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Key words : Staphylococcus aureus, MRSA, endocarditis, septicemia
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| Infective endocarditis involving the aortic valve. Red-colored verruca is attached and the cusp is ulcerated (gross findings). | Heavily basophilic cocci are densely colonized in the destroyed valvular tissue (HE, low power). | |
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| Colonies of heavily basophilic cocci are seen in the fibrinous matrix (HE, high power). MRSA was cultured from the blood. | Septic microabscess formed in the myocardium is demonstrated. Neutrophils are clustered around the Gram-positive coccal colony (Gram). | |
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