Case 81. Blastomycosis of lung (48 y-o M)
Fatally progressive lung lesion in an American black
Key words : Blastomyces dermatitidis, progressive lung lesion
Infiltration of neutrophils and macrophages is evident in the diffusely involved lung (HE). Systemic dissemination of the fungi led the patient to death.   Large-sized yeasts, Blastomyces dermatitidis, reveal thick cell wall and internal eosinophilic cytoplasm, with a haloe formed between these two (HE, high power).
The cell wall is stained black by Grocott's silver. Budding growth pattern of the yeast is evident.