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The aim of this 7-chapter, single-author textbook entitled
"Pathology of Skin Infections" is to overview and illustrate
features of skin infections caused by bacteria, fungi, viruses, protozoa,
helminth and arthropods. Histological features based on hematoxylin
eosin staining and gross appearance comprise the major part of the
illustrations. Immunostaining using the indirect immunoperoxidase or
amino acid polymer method and non-isotopic in situ hybridization technique
were employed when necessary.
The indirect immunoperoxidase method using 1:500 to 1:1,000 diluted
patients’ serum as a primary antibody was also applied to localize pathogens
within the lesion fixed in 10-20% formalin and embedded in paraffin.
Papanicolaou- or Giemsa-stained cytology evaluation, as well as electron
microscopic analysis and polymerase chain reaction (PCR), were also
performed upon request.
The prompt and precise diagnosis of emerging and re-emerging infectious
diseases, nosocomial infections and sexually transmitted infections
has an important socio-public impact for the prevention of unnecessary
transmission of microorganisms. The skin may function as a mirror of
The author has tried to include information and unique episodes that
have occurred in Japan and are picked up as notes for the readers’ curiosity
and intelligence. He, as a diagnostic pathologist, sincerely hopes that
this textbook helps pathologists, dermatologists and other clinicians
make an appropriate diagnosis of skin infections. He strongly believes
that proper diagnosis may lead patients to proper treatment and cure,
and may contribute to human society by preventing infectious disorders.
Table of Contents:
Chapter I. Techniques for Visualization of Microbes within the Lesions
Chapter II. Bacterial Infections
Chapter III. Fungal infections
Chapter IV. Viral Infections
Chapter V. Protozoan Infections
Chapter VI. Helminthic Infestations
Chapter VII. Arthropod Infestations
Profile of the Author